FOXP4 antibody (Middle Region)

Catalog No. ABIN2777345

This Rabbit Polyclonal antibody specifically detects FOXP4 in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Guinea Pig, Rabbit, Dog, Horse and Zebrafish (Danio rerio)and has been mentioned in 1 publication.

Quick Overview for FOXP4 antibody (Middle Region) (ABIN2777345)

Target: FOXP4 (Forkhead Box P4 (FOXP4))

Reactivity: Human, Rat, Mouse, Cow, Guinea Pig, Rabbit, Dog, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXP4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FOXP4 Antibody

Binding Specificity: Middle Region

Sequence: PRLSPPQYSH QVQVKEEPAE AEEDRQPGPP LGAPNPSASG PPEDRDLEEE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against FOXP4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FOXP4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 680 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-FOXP4 antibody (ABIN2777345)

Tuovinen, Kekäläinen, Rossi, Puntila, Arstila: "Cutting edge: human CD4-CD8- thymocytes express FOXP3 in the absence of a TCR." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 6, pp. 3651-4, (2008) (PubMed).

Target Details for FOXP4

Target: FOXP4 (Forkhead Box P4 (FOXP4))

Alternative Name: FOXP4

Background: FOXP4 belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Many members of the forkhead box gene family, including members of subfamily P, have roles in mammalian oncogenesis. FOXP4 may play a role in the development of tumors of the kidney and larynx. This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Many members of the forkhead box gene family, including members of subfamily P, have roles in mammalian oncogenesis. This gene may play a role in the development of tumors of the kidney and larynx. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.
Alias Symbols: FLJ40908, FLJ44184, hFKHLA
Protein Interaction Partner: SOX2, MKI67, SUMO2, UBC, FOXP1, FOXP4, FOXP2,
Protein Size: 680

Molecular Weight: 73 kDa

Gene ID: 116113

NCBI Accession: NM_138457, NP_612466

UniProt: Q8IW55