AEBP1 antibody (N-Term)

Catalog No. ABIN2777370

This Rabbit Polyclonal antibody specifically detects AEBP1 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Guinea Pig, Horse, Rabbit, Cow and Dogand has been mentioned in 1 publication.

Quick Overview for AEBP1 antibody (N-Term) (ABIN2777370)

Target: AEBP1 (AE Binding Protein 1 (AEBP1))

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Rabbit, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AEBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-AEBP1 Antibody

Binding Specificity: N-Term

Sequence: VPPEKTKDKG KKGKKDKGPK VPKESLEGSP RPPKKGKEKP PKATKKPKEK

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against AEBP1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AEBP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1158 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-AEBP1 antibody (ABIN2777370)

Kim, Gieske, Trudgen, Hudgins-Spivey, Kim, Krust, Chambon, Jeong, Blalock, Ko: "Identification of estradiol/ER?-regulated genes in the mouse pituitary." in: The Journal of endocrinology, Vol. 210, Issue 3, pp. 309-21, (2011) (PubMed).

Target Details for AEBP1

Target: AEBP1 (AE Binding Protein 1 (AEBP1))

Alternative Name: AEBP1

Background: The adipocyte enhancer binding protein 1 (AEBP1) is a transcriptional repressor with carboxypeptidase (CP) activity. This protein binds to a regulatory sequence, adipocyte enhancer 1 (AE-1), located in the proximal promoter region of the adipose P2 (aP2) gene, which encodes the adipocyte fatty-acid binding protein. It is characterized as a member of the regulatory B-like CP family. This protein seems to be activated by a novel mechanism, whereby the direct binding of DNA enhances its protease activity. AEBP1 may play a role in differentiated vascular smooth muscle cells.
Alias Symbols: ACLP
Protein Interaction Partner: GRB2, TCF3,
Protein Size: 1158

Molecular Weight: 131 kDa

Gene ID: 165

NCBI Accession: NM_001129, NP_001120

UniProt: Q14113