ZNF384 antibody (Middle Region)
Quick Overview for ZNF384 antibody (Middle Region) (ABIN2777372)
Target
See all ZNF384 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Sequence
- KKKRMLESGL PEMNDPYVLS PEDDDDHQKD GKTYRCRMCS LTFYSKSEMQ
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Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%
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Characteristics
- This is a rabbit polyclonal antibody against ZNF384. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ZNF384
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 500 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ZNF384 (Zinc Finger Protein 384 (ZNF384))
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Alternative Name
- ZNF384
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Background
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The specific function of this protein remains unknownThis gene contains long CAG trinucleotide repeats coding consecutive glutamine residues. The gene product may functions as a transcription factor, with a potential role in the regulation of neurodevelopment or neuroplasticity. The protein appears to bind and regulate the promoters of MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Multiple transcript variants encoding several isoforms have been found for this gene.
Alias Symbols: CAGH1, CAGH1A, CIZ, ERDA2, NMP4, NP, TNRC1
Protein Interaction Partner: SOX2, UBC, OPTN, tat, HOXC9, CEBPE, TAF15, ZYX, PCBP1, VIM,
Protein Size: 500 -
Molecular Weight
- 54 kDa
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Gene ID
- 171017
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NCBI Accession
- NM_001039919, NP_001035008
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UniProt
- A8MQD1
Target
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