RYBP antibody (Middle Region)

Catalog No. ABIN2777441

This Rabbit Polyclonal antibody specifically detects RYBP in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for RYBP antibody (Middle Region) (ABIN2777441)

Target: RYBP (RING1 and YY1 Binding Protein (RYBP))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RYBP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RYBP Antibody

Binding Specificity: Middle Region

Sequence: ATPPPPKKEK KEKVEKQDKE KPEKDKEISP SVTKKNTNKK TKPKSDILKD

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RYBP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RYBP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 228 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RYBP

Target: RYBP (RING1 and YY1 Binding Protein (RYBP))

Alternative Name: RYBP

Background: RYBP contains 1 RanBP2-type zinc finger. RYBP may be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1. In tumor cell lines, it may induce apoptosis.
Alias Symbols: AAP1, DEDAF, YEAF1
Protein Interaction Partner: RING1, EED, RNF2, BMI1, GABPB2, KDM2B, YY1, GABPB1, CSNK2A2, Dlg4, UBC, PCGF5, PCGF6, L3MBTL2, FBRS, BCORL1, FBRSL1, BCOR, RYBP, MGA, CBX3, WDR5, PCGF3, USP7, PCGF2, TFDP1, SKP1, E2F6, CSNK2B, PCGF1, CSNK2A1, ELAVL1, ZFP42, SOCS2, CBX2, FADD, CASP8, CASP1
Protein Size: 228

Molecular Weight: 25 kDa

Gene ID: 23429

NCBI Accession: NM_012234, NP_036366

UniProt: Q8N488