GATA3 antibody (N-Term)

Catalog No. ABIN2777460

The Rabbit Polyclonal anti-GATA3 antibody has been validated for WB and IHC. It is suitable to detect GATA3 in samples from Human, Mouse, Rat, Cow, Pig, Dog, Zebrafish (Danio rerio), Rabbit, Guinea Pig, Horse and Sheep.

Quick Overview for GATA3 antibody (N-Term) (ABIN2777460)

Target: GATA3 (GATA Binding Protein 3 (GATA3))

Reactivity: Human, Mouse, Rat, Cow, Pig, Dog, Zebrafish (Danio rerio), Rabbit, Guinea Pig, Horse, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GATA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GATA3 Antibody

Binding Specificity: N-Term

Sequence: MDAAQYPLPE EVDVLFNIDG QGNHVPPYYG NSVRATVQRY PPTHHGSQVC

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against GATA3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GATA3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 444 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GATA3

Target: GATA3 (GATA Binding Protein 3 (GATA3))

Alternative Name: GATA3

Background: GATA3 is crucially involved in IL-5 gene transcription in human peripheral CD4-positive t cells. This gene is involved in growth control and the maintenance of the differentiated state in epithelial cells and may contribute to tumorigenesis in breast cancer.
Alias Symbols: HDR, MGC2346, MGC5199, MGC5445, HDRS
Protein Interaction Partner: PSMA3, FOXP3, USP21, UBC, SPI1, BRCA1, MYB, REPIN1, SP1, TBX21, HDAC5, HDAC4, HDAC3, RARB, MDM2, BMI1, MED1, ZFPM2, SATB1, TAL1, LMO1, LMO2, ETS2, ETS1,
Protein Size: 444

Molecular Weight: 48 kDa

Gene ID: 2625

NCBI Accession: NM_002051, NP_002042

UniProt: P23771

Pathways: Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation