GFI1 antibody (N-Term)

Catalog No. ABIN2777468

This anti-GFI1 antibody is a Rabbit Polyclonal antibody detecting GFI1 in WB. Suitable for Human, Rat, Mouse, Cow, Dog, Rabbit, Guinea Pig and Horse.

Quick Overview for GFI1 antibody (N-Term) (ABIN2777468)

Target: GFI1 (Growth Factor Independent 1 (GFI1))

Reactivity: Human, Rat, Mouse, Cow, Dog, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GFI1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GFI1 Antibody

Binding Specificity: N-Term

Sequence: MPRSFLVKSK KAHSYHQPRS PGPDYSLRLE NVPAPSRADS TSNAGGAKAE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GFI1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GFI1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 422 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GFI1

Target: GFI1 (Growth Factor Independent 1 (GFI1))

Alternative Name: GFI1

Background: GFI1 may be a transcription factor involved in regulating the expression of genes active in the S phase during cell cycle progression in T-cells. GFI1 may be involved in tumor progression. Defects in GFI1 are a cause of autosomal dominant severe congenital neutropenia (SCN) and dominant nonimmune chronic idiopathic neutropenia of adults (NI-CINA)
Alias Symbols: ZNF163, SCN2, GFI-1
Protein Interaction Partner: RELA, SPI1, CHAF1A, PICK1, PIAS2, RCOR1, KDM1A, HDAC2, PRDM5, HDAC1, EHMT2, PIAS3, RUNX1T1, ARIH2, UBC,
Protein Size: 422

Molecular Weight: 46 kDa

Gene ID: 2672

NCBI Accession: NM_005263, NP_005254

UniProt: Q99684