CNOT2 antibody (Middle Region)

Catalog No. ABIN2777548

This Rabbit Polyclonal antibody specifically detects CNOT2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for CNOT2 antibody (Middle Region) (ABIN2777548)

Target: CNOT2 (CCR4-NOT Transcription Complex, Subunit 2 (CNOT2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNOT2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CNOT2 Antibody

Binding Specificity: Middle Region

Sequence: PLAGRAPYVG MVTKPANEQS QDFSIHNEDF PALPGSSYKD PTSSNDDSKS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CNOT2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CNOT2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 540 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CNOT2

Target: CNOT2 (CCR4-NOT Transcription Complex, Subunit 2 (CNOT2))

Alternative Name: CNOT2

Background: The CCR4-NOT complex functions as general transcription regulation complex.
Alias Symbols: CDC36, HSPC131, NOT2, NOT2H
Protein Interaction Partner: UBC, RNF219, NLK, CNOT6L, CNOT6, VCP, Cnot3, NCOR2, NCOR1, HDAC3, GPS2, DDB1, CNOT1, CNOT8, CDC39,
Protein Size: 540

Molecular Weight: 60 kDa

Gene ID: 4848

NCBI Accession: NM_014515, NP_055330

UniProt: Q9NZN8

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance