T-Box 22 antibody (Middle Region)

Catalog No. ABIN2777562

This Rabbit Polyclonal antibody specifically detects T-Box 22 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Horse, Pig and Rabbitand has been mentioned in 1 publication.

Quick Overview for T-Box 22 antibody (Middle Region) (ABIN2777562)

Target: T-Box 22 (TBX22)

Reactivity: Human, Mouse, Rat, Cow, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This T-Box 22 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-T-Box 22 Antibody

Binding Specificity: Middle Region

Sequence: QSMHKYKPRV HVIEQGSSVD LSQIQSLPTE GVKTFSFKET EFTTVTAYQN

Predicted Reactivity: Cow: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 86%, Rabbit: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against TBX22. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TBX22

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 520 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-T-Box 22 antibody (ABIN2777562)

Suphapeetiporn, Tongkobpetch, Siriwan, Shotelersuk: "TBX22 mutations are a frequent cause of non-syndromic cleft palate in the Thai population." in: Clinical genetics, Vol. 72, Issue 5, pp. 478-83, (2007) (PubMed).

Target Details for T-Box 22

Target: T-Box 22 (TBX22)

Alternative Name: TBX22

Background: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis.This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CLPA, TBXX, dJ795G23.1, CPX
Protein Interaction Partner: VENTX, HSP90AA1, APP,
Protein Size: 520

Molecular Weight: 58 kDa

Gene ID: 50945

NCBI Accession: NM_016954, NP_058650

UniProt: Q9Y458