HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) (N-Term) antibody

Catalog No. ABIN2777583

The Rabbit Polyclonal anti- antibody has been validated for WB and IHC. It is suitable to detect in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) (N-Term) antibody (ABIN2777583)

Target: HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2)

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details

Binding Specificity: N-Term

Sequence: TGRVLLKEIL EQGLFSKVTL IGRRKLTFDE EAYKNVNQEV VDFEKLDDYA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HTATIP2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HTATIP2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 242 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2)

Alternative Name: HTATIP2

Target Type: Viral Protein

Background: CC3 (HTATIP2) is a member of the short-chain dehydrogenases/reductases (SDR) family. It is a novel serine/threonine kinase that phosphorylates the C-terminal domain (CTD) of the largest RNA polymerase II subunit and induces the expression of apoptosis related genes Bad and Siva, as well as metastasis suppressor NM23-H2. It also interacts with an estrogen receptor alpha-interacting coactivator CIA and regulates ERalpha-mediated c-myc transcription.
Alias Symbols: CC3, TIP30, SDR44U1
Protein Interaction Partner: UBC, NCOA5, ASF1A, ETS1,
Protein Size: 242

Molecular Weight: 27 kDa

Gene ID: 10553

NCBI Accession: NM_006410, NP_006401

UniProt: O15383