MXD4 antibody (N-Term)

Catalog No. ABIN2777585

This Rabbit Polyclonal antibody specifically detects MXD4 in IHC and WB. It exhibits reactivity toward Human, Mouse, Cow, Dog, Guinea Pig, Rabbit and Sheep.

Quick Overview for MXD4 antibody (N-Term) (ABIN2777585)

Target: MXD4 (MAX Dimerization Protein 4 (MXD4))

Reactivity: Human, Mouse, Cow, Dog, Guinea Pig, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MXD4 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Product Details anti-MXD4 Antibody

Binding Specificity: N-Term

Sequence: SLLILLEAAE YLERRDREAE HGYASVLPFD GDFAREKTKA AGLVRKAPNN

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against MXD4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MXD4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 209 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MXD4

Target: MXD4 (MAX Dimerization Protein 4 (MXD4))

Alternative Name: MXD4

Background: MXD4 is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.
Alias Symbols: MAD4, MST149, MSTP149, bHLHc12
Protein Interaction Partner: TCP10L, UBC, SHBG, SIN3A, MLX, MAX, SMC3,
Protein Size: 209

Molecular Weight: 24 kDa

Gene ID: 10608

NCBI Accession: NM_006454, NP_006445

UniProt: Q14582