ACAT2 antibody (Middle Region)

Catalog No. ABIN2777595

This anti-ACAT2 antibody is a Rabbit Polyclonal antibody detecting ACAT2 in WB and IHC. Suitable for Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse and Rabbit.

Quick Overview for ACAT2 antibody (Middle Region) (ABIN2777595)

Target: ACAT2 (Acetyl-CoA Acetyltransferase 2 (ACAT2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACAT2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ACAT2 Antibody

Binding Specificity: Middle Region

Sequence: SREDQDKVAV LSQNRTENAQ KAGHFDKEIV PVLVSTRKGL IEVKTDEFPR

Predicted Reactivity: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ACAT2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ACAT2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 397 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ACAT2

Target: ACAT2 (Acetyl-CoA Acetyltransferase 2 (ACAT2))

Alternative Name: ACAT2

Background: Acetyl-Coenzyme A acetyltransferase 2 is an enzyme involved in lipid metabolism. Reported patients with ACAT2 deficiency have shown severe mental retardation and hypotonus. The ACAT2 gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation.
Alias Symbols: ACAT2, ACTL
Protein Interaction Partner: CDKN2A, HBA1, CLU, SYK, BLOC1S6, SLC4A1AP, CA2, ANK1, RHAG, LYN, EPB41, CA4, CANX, SLC4A1, ACTC1, EPB42,
Protein Size: 397

Molecular Weight: 41 kDa

Gene ID: 39

NCBI Accession: NM_005891, NP_005882

UniProt: Q9BWD1