ACAT2 antibody (Middle Region)

Catalog No. ABIN2777596

This Rabbit Polyclonal antibody specifically detects ACAT2 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse and Saccharomyces cerevisiae.

Quick Overview for ACAT2 antibody (Middle Region) (ABIN2777596)

Target: ACAT2 (Acetyl-CoA Acetyltransferase 2 (ACAT2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACAT2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ACAT2 Antibody

Binding Specificity: Middle Region

Sequence: VLSQNRTENA QKAGHFDKEI VPVLVSTRKG LIEVKTDEFP RHGSNIEAMS

Predicted Reactivity: Cow: 79%, Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 79%, Rat: 79%, Yeast: 82%

Characteristics: This is a rabbit polyclonal antibody against ACAT2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ACAT2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 397 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ACAT2

Target: ACAT2 (Acetyl-CoA Acetyltransferase 2 (ACAT2))

Alternative Name: ACAT2

Background: Acetyl-Coenzyme A acetyltransferase 2 is an enzyme involved in lipid metabolism. Reported patients with ACAT2 deficiency have shown severe mental retardation and hypotonus. The ACAT2 gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation.
Protein Interaction Partner: LNX1, ACAT2, UBC, SUMO2, OLA1, TUBB3, PAPSS1, UBA3, PKM, HMGB3, HEXA, FH, ALDH9A1, AHCY, BAG3, TTC39C, PSAT1, SSU72, DAK, VASP, TERF1, CDX2, CSNK2A1,
Protein Size: 397

Molecular Weight: 44 kDa

Gene ID: 39

NCBI Accession: NM_005891, NP_005882

UniProt: Q16146