DLX1 antibody (C-Term)

Catalog No. ABIN2777637

This Rabbit Polyclonal antibody specifically detects DLX1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit and Cowand has been mentioned in 1 publication.

Quick Overview for DLX1 antibody (C-Term) (ABIN2777637)

Target: DLX1 (Distal-Less Homeobox Protein 1 (DLX1))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLX1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DLX1 Antibody

Binding Specificity: C-Term

Sequence: KFKKLMKQGG AALEGSALAN GRALSAGSPP VPPGWNPNSS SGKGSGGNAG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DLX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DLX1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 255 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-DLX1 antibody (ABIN2777637)

Bökenkamp, van Brempt, van Munsteren, van den Wijngaert, de Hoogt, Finos, Goeman, Groot, Poelmann, Blom, DeRuiter: "Dlx1 and Rgs5 in the ductus arteriosus: vessel-specific genes identified by transcriptional profiling of laser-capture microdissected endothelial and smooth muscle cells." in: PLoS ONE, Vol. 9, Issue 1, pp. e86892, (2014) (PubMed).

Target Details for DLX1

Target: DLX1 (Distal-Less Homeobox Protein 1 (DLX1))

Alternative Name: DLX1

Background: DLX1 is a member of a homeobox transcription factor family. It is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-{beta} superfamily members. DLX1 may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain.This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-{beta} superfamily members. The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain. This gene is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 2. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: -
Protein Interaction Partner: SMAD4,
Protein Size: 255

Molecular Weight: 27 kDa

Gene ID: 1745

NCBI Accession: NM_178120, NP_835221

UniProt: P56177