KDM3A antibody (C-Term)

Catalog No. ABIN2777661

The Rabbit Polyclonal anti-KDM3A antibody has been validated for WB and IHC. It is suitable to detect KDM3A in samples from Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio). There is 1 publication available.

Quick Overview for KDM3A antibody (C-Term) (ABIN2777661)

Target: KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM3A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-KDM3A Antibody

Binding Specificity: C-Term

Sequence: HNLYSCIKVA EDFVSPEHVK HCFWLTQEFR YLSQTHTNHE DKLQVKNVIY

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against JMJD1A. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human JMJD1A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1321 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-KDM3A antibody (ABIN2777661)

Zhou, Sun, Ellen, Chen, Costa: "Arsenite alters global histone H3 methylation." in: Carcinogenesis, Vol. 29, Issue 9, pp. 1831-6, (2008) (PubMed).

Target Details for KDM3A

Target: KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))

Alternative Name: JMJD1A

Background: JMJD1A is a zinc finger protein that contains a jumonji domain.
Alias Symbols: TSGA, JMJD1, JHDM2A, JHMD2A, JMJD1A
Protein Interaction Partner: RIPK2, HIST2H3C, CBX2, CBX4, AR, HIF1A, UBC, MYOCD, MKL1, MKL2, ETV2, TCEAL1,
Protein Size: 1321

Molecular Weight: 147 kDa

Gene ID: 55818

NCBI Accession: NM_018433, NP_060903

UniProt: Q53S72

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Warburg Effect