LIM Domain Binding 2 Protein antibody (N-Term)
Quick Overview for LIM Domain Binding 2 Protein antibody (N-Term) (ABIN2777701)
Target
See all LIM Domain Binding 2 Protein (LDB2) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- DDATLTLSFC LEDGPKRYTI GRTLIPRYFS TVFEGGVTDL YYILKHSKES
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Predicted Reactivity
- Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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Characteristics
- This is a rabbit polyclonal antibody against LDB2. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human LDB2
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 373 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- LIM Domain Binding 2 Protein (LDB2) (LIM Domain Binding 2 (LDB2))
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Alternative Name
- LDB2
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Background
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LDB2 belongs to the LDB family. LDB2 binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. LIM domains are required for both inhibitory effects on LIM homeodomain transcription factors and synergistic transcriptional activation events. The inhibitory actions of the LIM domain can often be overcome by the LIM co-regulators known as CLIM2, LDB2 and NLI. LIM homeoproteins and CLIMs are involved in a variety of developmental processes.
Alias Symbols: LDB1, CLIM1
Protein Interaction Partner: LHX4, RILP, LMO3, RASIP1, SSBP3, SSBP2, LMO4, TSNAX, UBC, SSBP4, ISL1, LHX9, RLIM,
Protein Size: 373 -
Molecular Weight
- 43 kDa
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Gene ID
- 9079
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NCBI Accession
- NM_001290, NP_001281
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UniProt
- O43679
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Pathways
- Stem Cell Maintenance
Target
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