PFDN1 antibody (N-Term)

Catalog No. ABIN2777713

This Rabbit Polyclonal antibody specifically detects PFDN1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig and Horse.

Quick Overview for PFDN1 antibody (N-Term) (ABIN2777713)

Target: PFDN1 (Prefoldin Subunit 1 (PFDN1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PFDN1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PFDN1 Antibody

Binding Specificity: N-Term

Sequence: MAAPVDLELK KAFTELQAKV IDTQQKVKLA DIQIEQLNRT KKHAHLTDTE

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PFDN1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PFDN1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 122 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PFDN1

Target: PFDN1 (Prefoldin Subunit 1 (PFDN1))

Alternative Name: PFDN1

Background: Prefoldin 1 is a heterohexameric chaperone protein which assists in the correct folding of other proteins. It binds specifically to cytosolic chaperonin and transfers target proteins. Prefoldin may function by selectively targeting nascent actin and tubulin chains pending their transfer to cytosolic chaperonin for final folding and/or assembly. It promotes folding in an environment in which there are many competing pathways for nonnative proteins.
Alias Symbols: PDF, PFD1
Protein Interaction Partner: TSN, SH3GL1, PRPS1, PRKACB, PPP2CA, NRD1, PPP1R12A, HARS, FEN1, SETSIP, AARSD1, PUS1, P3H1, ELAC2, UGGT1, NSUN2, DPP8, PFDN5, MAPK7, TERT, FBXW4, UBC, METTL21B, PFDN6, NUBP2, PFDN4, PFDN2, IGBP1, CCDC85A, RMI1, JADE1, SPTBN4, FAM20C, BRK1, INPP5K, GIT1, S
Protein Size: 122

Molecular Weight: 14 kDa

Gene ID: 5201

NCBI Accession: NM_002622, NP_002613

UniProt: O60925

Pathways: Unfolded Protein Response