POU3F1 antibody (N-Term)

Catalog No. ABIN2777729

The Rabbit Polyclonal anti-POU3F1 antibody has been validated for WB and IHC. It is suitable to detect POU3F1 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig and Rabbit. There are 2+ publications available.

Quick Overview for POU3F1 antibody (N-Term) (ABIN2777729)

Target: POU3F1 (POU Class 3 Homeobox 1 (POU3F1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POU3F1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-POU3F1 Antibody

Binding Specificity: N-Term

Sequence: YLPRGPGGGA GGTGPLMHPD AAAAAAAAAE RLHAGAAYRE VQKLMHHEWL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against POU3F1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human POU3F1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 448 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-POU3F1 antibody (ABIN2777729)

Hashimoto, Tatsumi, Takeda, Naka, Ogane, Kameda, Kawachi, Shimizu, Sakai, Kamoshida: "Expression of organic anion-transporting polypeptide 1A2 and organic cation transporter 6 as a predictor of pathologic response to neoadjuvant chemotherapy in triple negative breast cancer." in: Breast cancer research and treatment, Vol. 145, Issue 1, pp. 101-11, (2014) (PubMed).

Sumiyama, Washio-Watanabe, Ono, Yoshida, Hayakawa, Ueda: "Human class III POU genes, POU3F1 and POU3F3, map to chromosomes 1p34.1 and 3p14.2." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 9, Issue 2, pp. 180-1, (1998) (PubMed).

Target Details for POU3F1

Target: POU3F1 (POU Class 3 Homeobox 1 (POU3F1))

Alternative Name: POU3F1

Background: POU3F1 is a member of the POU domain family of proteins, and regulates events during neurogenesis and myelination.
Alias Symbols: OCT6, OTF6, SCIP
Protein Interaction Partner: HMGA1, POU3F4, HMGB2,
Protein Size: 448

Molecular Weight: 45 kDa

Gene ID: 5453

NCBI Accession: NM_002699, NP_002690

UniProt: Q03052