PURA antibody (N-Term)
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- Target See all PURA Antibodies
- PURA (Purine-Rich Element Binding Protein A (PURA))
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PURA antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MADRDSGSEQ GGAALGSGGS LGHPGSGSGS GGGGGGGGGG GGSGGGGGGA
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
- Characteristics
- This is a rabbit polyclonal antibody against PURA. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PURA
- Top Product
- Discover our top product PURA Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 322 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PURA (Purine-Rich Element Binding Protein A (PURA))
- Alternative Name
- PURA (PURA Products)
- Synonyms
- CAGER-1 antibody, Pur-alpha antibody, ssCRE-BP antibody, PUR-ALPHA antibody, PUR1 antibody, PURALPHA antibody, zgc:103411 antibody, pur-alpha antibody, pur1 antibody, puralpha antibody, purine-rich element binding protein A antibody, purine rich element binding protein A antibody, purine-rich element binding protein Aa antibody, purine-rich element binding protein A L homeolog antibody, pura antibody, Pura antibody, PURA antibody, puraa antibody, pura.L antibody
- Background
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This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.
Alias Symbols: PUR1, MRD31, PURALPHA, PUR-ALPHA
Protein Interaction Partner: RAF1, UBC, LIN28B, LIN28A, BMI1, TARDBP, IGSF8, ICAM1, IL7R, ZNF638, DDX23, RFC3, RFC2, RB1, PURB, POLA1, CAND1, CUL1, CUL3, EIF2AK2, POU5F1, MEPCE, HNRNPA1, ADAP1, CCNT1, E2F1, SP1, YBX1, CDK5, CNBP, Jvgp5,
Protein Size: 322 - Molecular Weight
- 35 kDa
- Gene ID
- 5813
- NCBI Accession
- NM_005859, NP_005850
- UniProt
- Q00577
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