TOLLIP antibody (N-Term)

Catalog No. ABIN2777827

The Rabbit Polyclonal anti-TOLLIP antibody has been validated for WB. It is suitable to detect TOLLIP in samples from Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Guinea Pig, Horse, Rabbit and Dog.

Quick Overview for TOLLIP antibody (N-Term) (ABIN2777827)

Target: TOLLIP (Toll Interacting Protein (TOLLIP))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Guinea Pig, Horse, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TOLLIP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TOLLIP Antibody

Binding Specificity: N-Term

Sequence: MATTVSTQRG PVYIGELPQD FLRITPTQQQ QQIQLDAQAA QQLQYGGTVG

Predicted Reactivity: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against Tollip. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 274 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TOLLIP

Target: TOLLIP (Toll Interacting Protein (TOLLIP))

Alternative Name: Tollip

Background: Tollip is a component of the signaling pathway of IL-1 and Toll-like receptors.Tollip inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Tollip inhibits IRAK1 phosphorylation and kinase activity.
Alias Symbols: 4930403G24Rik, 4931428G15Rik
Protein Interaction Partner: Irak1, Htt, Tom1,
Protein Size: 274

Molecular Weight: 30 kDa

Gene ID: 54473

NCBI Accession: NM_023764, NP_076253

UniProt: Q9QZ06