Sp2 antibody (N-Term)

Catalog No. ABIN2777870

This Rabbit Polyclonal antibody specifically detects Sp2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Pig, Horse, Dog, Rabbit and Saccharomyces cerevisiae.

Quick Overview for Sp2 antibody (N-Term) (ABIN2777870)

Target: Sp2 (Sp2 Transcription Factor (Sp2))

Reactivity: Human, Mouse, Rat, Cow, Pig, Horse, Dog, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sp2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Sp2 Antibody

Binding Specificity: N-Term

Sequence: QDSQPSPLAL LAATCSKIGP PAVEAAVTPP APPQPTPRKL VPIKPAPLPL

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 91%

Characteristics: This is a rabbit polyclonal antibody against SP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SP2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 249 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Sp2

Target: Sp2 (Sp2 Transcription Factor (Sp2))

Alternative Name: SP2

Background: SP2 is a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters.
Alias Symbols: -
Protein Interaction Partner: BANP, MCM7, FHL2, HECW2, SOX2, APP, IRF1, ESR1, Nkx3-1, NR0B2, E2F1,
Protein Size: 249

Molecular Weight: 27 kDa

Gene ID: 6668

NCBI Accession: NM_003110

UniProt: Q02086