TADA2L antibody (C-Term)

Catalog No. ABIN2777908

The Rabbit Polyclonal anti-TADA2L antibody has been validated for WB. It is suitable to detect TADA2L in samples from Human.

Quick Overview for TADA2L antibody (C-Term) (ABIN2777908)

Target: TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TADA2L antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TADA2L Antibody

Binding Specificity: C-Term

Sequence: RRQADIDSGL SPSIPMASNS GRRSAPPLNL TGLPGTEKLN EKEKELCQMV

Predicted Reactivity: Chicken: 100%

Characteristics: This is a rabbit polyclonal antibody against TADA2L. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TADA2L

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 443 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TADA2L

Target: TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))

Alternative Name: TADA2L

Background: Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. TADA2L is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex.
Alias Symbols: ADA2, ADA2A, FLJ12705, KL04P, TADA2L, hADA2
Protein Interaction Partner: MFAP1, MAGOH, KPNA2, FBF1, PRPF31, PPP1R16B, ZFYVE26, SF3A3, FARS2, MTX2, EIF4E2, FAM127C, KLHL38, TTC9C, ZNF564, TEKT4, LOC149950, KLC4, TTC23, GPSM3, CDCA7L, C1orf109, CCHCR1, PRKAB2, ARNT2, USP22, TADA3, HNF4A, LYN, HSP90AA1, KAT2B, MCPH1, PAXIP1, SUPT
Protein Size: 443

Molecular Weight: 51 kDa

Gene ID: 6871

NCBI Accession: NM_001488, NP_001479

UniProt: O75478

Pathways: Chromatin Binding