TGFB1I1 antibody (Middle Region)

Catalog No. ABIN2777947

This Rabbit Polyclonal antibody specifically detects TGFB1I1 in WB and IHC. It exhibits reactivity toward Human, Rat, Mouse, Dog, Cow, Rabbit, Horse, Goat and Guinea Pigand has been mentioned in 1 publication.

Quick Overview for TGFB1I1 antibody (Middle Region) (ABIN2777947)

Target: TGFB1I1 (Transforming Growth Factor beta 1 Induced Transcript 1 (TGFB1I1))

Reactivity: Human, Rat, Mouse, Dog, Cow, Rabbit, Horse, Goat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TGFB1I1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TGFB1I1 Antibody

Binding Specificity: Middle Region

Sequence: PEPTGKGSLD TMLGLLQSDL SRRGVPTQAK GLCGSCNKPI AGQVVTALGR

Predicted Reactivity: Cow: 100%, Dog: 93%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TGFB1I1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human TGFB1I1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 444 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TGFB1I1 antibody (ABIN2777947)

Miyoshi, Ishiguro, Uemura, Fujinami, Miyamoto, Miyoshi, Kitamura, Kubota: "Expression of AR associated protein 55 (ARA55) and androgen receptor in prostate cancer." in: The Prostate, Vol. 56, Issue 4, pp. 280-6, (2003) (PubMed).

Target Details for TGFB1I1

Target: TGFB1I1 (Transforming Growth Factor beta 1 Induced Transcript 1 (TGFB1I1))

Alternative Name: TGFB1I1

Background: The TGFB1I1 gene encodes a protein that is a key element in the transduction of signals from the cell surface to the nucleus under oxidative stress-review. Higher gene expression may result in unfavorable recurrence-free survival and overall survival in hormone-refractory prostate cancer.
Alias Symbols: ARA55, HIC-5, HIC5, TSC-5
Protein Interaction Partner: HSPB2, HSPB1, CBLC, SMAD4, SMAD3, Pparg, CDKN2B, PLA2G3, HIPK3, CBLB, NCF1, GP6, TRAF4, SMAD7, GP1BB, UBQLN4, NEDD4L, UBC, PTK2, MAPK15, GIT2, SDC4, GIT1, SVIL, EP300, CRKL, PTK2B, PTPN12, AR, ITGA4, TGFBR2, FKBP1A, NR3C1, SLC6A3, VCL, CSK, PXN, CCNA1, VH
Protein Size: 444

Molecular Weight: 48 kDa

Gene ID: 7041

NCBI Accession: NM_015927, NP_057011

UniProt: B2R8D5

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, VEGF Signaling