TGFB1I1 antibody (AA 138-200)

Catalog No. ABIN7172818

Product Details anti-TGFB1I1 Antibody

Target: TGFB1I1 (Transforming Growth Factor beta 1 Induced Transcript 1 (TGFB1I1))

Binding Specificity: AA 138-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TGFB1I1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Transforming growth factor beta-1-induced transcript 1 protein (138-200AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TGFB1I1

Target: TGFB1I1 (Transforming Growth Factor beta 1 Induced Transcript 1 (TGFB1I1))

Alternative Name: TGFB1I1 (TGFB1I1 Products)

Synonyms: TGFB1I1 antibody, hic5 antibody, ara55 antibody, hic-5 antibody, tsc-5 antibody, ARA55 antibody, HIC-5 antibody, HIC5 antibody, TSC-5 antibody, Hic5 antibody, Ara55 antibody, Hic-5 antibody, ara-55 antibody, transforming growth factor beta 1 induced transcript 1 antibody, transforming growth factor beta 1 induced transcript 1 L homeolog antibody, TGFB1I1 antibody, tgfb1i1 antibody, Tgfb1i1 antibody, tgfb1i1.L antibody

Background:

Background: Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. May also regulate SLC6A3 and SLC6A4 targeting to the plasma membrane hence regulating their activity. In the nucleus, functions as a nuclear receptor coactivator regulating glucocorticoid, androgen, mineralocorticoid and progesterone receptor transcriptional activity. May play a role in the processes of cell growth, proliferation, migration, differentiation and senescence. May have a zinc-dependent DNA-binding activity.

Aliases: Androgen receptor coactivator 55 kDa protein antibody, Androgen receptor coactivator ARA55 antibody, Androgen receptor-associated protein of 55 kDa antibody, ARA55 antibody, Hic-5 antibody, Hydrogen peroxide-inducible clone 5 protein antibody, Tgfb1i1 antibody, TGFI1_HUMAN antibody, Transforming growth factor beta 1 induced transcript 1 antibody, Transforming growth factor beta-1-induced transcript 1 protein antibody, TSC 5 antibody

UniProt: O43294

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, VEGF Signaling