Claudin 17 antibody (Middle Region)

Catalog No. ABIN2778040

The Rabbit Polyclonal anti-Claudin 17 antibody has been validated for WB and IHC. It is suitable to detect Claudin 17 in samples from Human, Mouse, Rat, Dog, Cow, Pig, Horse, Sheep, Guinea Pig and Rabbit. There is 1 publication available.

Quick Overview for Claudin 17 antibody (Middle Region) (ABIN2778040)

Target: Claudin 17 (CLDN17)

Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Horse, Sheep, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 17 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Claudin 17 Antibody

Binding Specificity: Middle Region

Sequence: KQVQCTGSNE RAKAYLLGTS GVLFILTGIF VLIPVSWTAN IIIRDFYNPA

Predicted Reactivity: Cow: 85%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%, Sheep: 85%

Characteristics: This is a rabbit polyclonal antibody against CLDN17. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CLDN17

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 224 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Claudin 17 antibody (ABIN2778040)

Michlig, Damak, Le Coutre: "Claudin-based permeability barriers in taste buds." in: The Journal of comparative neurology, Vol. 502, Issue 6, pp. 1003-11, (2007) (PubMed).

Target Details for Claudin 17

Target: Claudin 17 (CLDN17)

Alternative Name: CLDN17

Background: CLDN17, clustered with CLDN8 at human chromosome 21q22.11, is a four-transmembrane protein with WWCC motif, defined by W-X(17-22)-W-X(2)-C-X(8-10)-C.
Protein Interaction Partner: LNX1,
Protein Size: 224

Molecular Weight: 25 kDa

Gene ID: 26285

NCBI Accession: NM_012131, NP_036263

UniProt: P56750

Pathways: Cell-Cell Junction Organization, Hepatitis C