Claudin 9 antibody (C-Term)

Catalog No. ABIN2778042

This Rabbit Polyclonal antibody specifically detects Claudin 9 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Guinea Pig and Horse and has been mentioned in 2+ publications.

Quick Overview for Claudin 9 antibody (C-Term) (ABIN2778042)

Target: Claudin 9 (CLDN9)

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 9 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Claudin 9 Antibody

Binding Specificity: C-Term

Sequence: WAAAALLMLG GGLLCCTCPP PQVERPRGPR LGYSIPSRSG ASGLDKRDYV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CLDN9. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CLDN9

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 217 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Claudin 9 antibody (ABIN2778042)

Carrozzino, Pugnale, Féraille, Montesano: "Inhibition of basal p38 or JNK activity enhances epithelial barrier function through differential modulation of claudin expression." in: American journal of physiology. Cell physiology, Vol. 297, Issue 3, pp. C775-87, (2009) (PubMed).

Abuazza, Becker, Williams, Chakravarty, Truong, Lin, Baum: "Claudins 6, 9, and 13 are developmentally expressed renal tight junction proteins." in: American journal of physiology. Renal physiology, Vol. 291, Issue 6, pp. F1132-41, (2006) (PubMed).

Target Details for Claudin 9

Target: Claudin 9 (CLDN9)

Alternative Name: CLDN9

Background: CLDN9 is a member of claudin family. It is a four-transmembrane protein with WWCC motif, defined by W-X(17-22)-W-X(2)-C-X(8-10)-C.
Protein Size: 217

Molecular Weight: 24 kDa

Gene ID: 9080

NCBI Accession: NM_020982, NP_066192

UniProt: O95484

Pathways: Cell-Cell Junction Organization, Hepatitis C