Claudin 15 antibody (Middle Region)

Catalog No. ABIN2778053

The Rabbit Polyclonal anti-Claudin 15 antibody is suitable to detect Claudin 15 in samples from Human, Cow, Horse, Dog and Pig. It has been validated for WB.

Quick Overview for Claudin 15 antibody (Middle Region) (ABIN2778053)

Target: Claudin 15 (CLDN15)

Reactivity: Human, Cow, Horse, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 15 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Claudin 15 Antibody

Binding Specificity: Middle Region

Sequence: LSGYIQACRA LMITAILLGF LGLLLGIAGL RCTNIGGLEL SRKAKLAATA

Predicted Reactivity: Cow: 93%, Dog: 92%, Horse: 86%, Human: 100%, Pig: 93%

Characteristics: This is a rabbit polyclonal antibody against CLDN15. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CLDN15

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 228 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Claudin 15

Target: Claudin 15 (CLDN15)

Alternative Name: CLDN15

Background: CLDN15 plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Alias Symbols: FLJ42715, MGC19536
Protein Interaction Partner: GEM,
Protein Size: 228

Molecular Weight: 24 kDa

Gene ID: 24146

NCBI Accession: NM_014343, NP_055158

UniProt: P56746

Pathways: Cell-Cell Junction Organization, Hepatitis C