USP3 antibody (Middle Region)

Catalog No. ABIN2778069

The Rabbit Polyclonal anti-USP3 antibody has been validated for WB. It is suitable to detect USP3 in samples from Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit, Horse, Pig and Zebrafish (Danio rerio).

Quick Overview for USP3 antibody (Middle Region) (ABIN2778069)

Target: USP3 (Ubiquitin Specific Peptidase 3 (USP3))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit, Horse, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-USP3 Antibody

Binding Specificity: Middle Region

Sequence: IEQFCCYFKE LPAVELRNGK TAGRRTYHTR SQGDNNVSLV EEFRKTLCAL

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 93%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against USP3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human USP3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 520 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for USP3

Target: USP3 (Ubiquitin Specific Peptidase 3 (USP3))

Alternative Name: USP3

Background: USP3 is a novel human ubiquitin-specific protease. The USP3 protein is a functional ubiquitin-specific protease in vitro, and is able to inhibit ubiquitin-dependent degradation of both an N-end Rule substrate and abnormal endogenous proteins in yeast. USP3 is also only the second known ubiquitin-specific protease capable of efficiently cleaving a ubiquitin-proline bond.
Alias Symbols: MGC129878, MGC129879, SIH003, UBP
Protein Interaction Partner: UBC, IFIH1, DDX58, TXNDC17, SH3BGRL3, TXLNG, ZFAND6, ATP6V1H, ELAVL1, TOR1AIP2, PRRC2B, NXN, RIMBP2, WDTC1, GNA13, EIF3I, EIF3H, EIF3G, EIF3F, EIF3D, EIF3C, EIF3B, EIF3A, PKLR, LRP1, GNAL, EIF4G1, CBR3,
Protein Size: 520

Molecular Weight: 59 kDa

Gene ID: 9960

NCBI Accession: NM_006537, NP_006528

UniProt: Q9Y6I4