PARP9 antibody (N-Term)

Catalog No. ABIN2778121

This Rabbit Polyclonal antibody specifically detects PARP9 in WB. It exhibits reactivity toward Human.

Quick Overview for PARP9 antibody (N-Term) (ABIN2778121)

Target: PARP9 (Poly (ADP-Ribose) Polymerase Family, Member 9 (PARP9))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PARP9 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PARP9 Antibody

Binding Specificity: N-Term

Sequence: LHGGGLALAL VKAGGFEIQE ESKQFVARYG KVSAGEIAVT GAGRLPCKQI

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against PARP9. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PARP9

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 854 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PARP9

Target: PARP9 (Poly (ADP-Ribose) Polymerase Family, Member 9 (PARP9))

Alternative Name: PARP9

Background: PARP9 contains 2 Macro domains and 1 PARP catalytic domain. PARP9 is overexpressed at significantly higher levels in fatal high-risk diffuse large B-cell lymphomas (DLB-CL) compared to cured low-risk tumors. Overexpression of PARP9 in B-cell lymphoma transfectants may promote malignant B-cell migration. The function of PARP9 remains unknown.
Alias Symbols: BAL, BAL1, DKFZp666B0810, DKFZp686M15238, FLJ26637, FLJ41418, MGC:7868
Protein Interaction Partner: UBC, DTX3L, PARP14, PARP1, RPA3, RPA2, RPA1, NAA25,
Protein Size: 854

Molecular Weight: 96 kDa

Gene ID: 83666

NCBI Accession: NM_031458, NP_113646

UniProt: Q8IXQ6