EPB42 antibody (Middle Region)

Catalog No. ABIN2778127

This Rabbit Polyclonal antibody specifically detects EPB42 in WB. It exhibits reactivity toward Human, Rat, Mouse, Guinea Pig, Cow, Dog, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for EPB42 antibody (Middle Region) (ABIN2778127)

Target: EPB42 (erythrocyte Membrane Protein Band 4.2 (EPB42))

Reactivity: Human, Rat, Mouse, Guinea Pig, Cow, Dog, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPB42 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EPB42 Antibody

Binding Specificity: Middle Region

Sequence: ISTKGVGSDR CEDITQNYKY PEGSLQEKEV LERVEKEKME REKDNGIRPP

Predicted Reactivity: Cow: 85%, Dog: 92%, Guinea Pig: 77%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 100%, Zebrafish: 75%

Characteristics: This is a rabbit polyclonal antibody against EPB42. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EPB42

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 721 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EPB42

Target: EPB42 (erythrocyte Membrane Protein Band 4.2 (EPB42))

Alternative Name: EPB42

Background: Erythrocyte membrane protein band 4.2 is an ATP-binding protein which may regulate the association of protein 3 with ankyrin. It probably has a role in erythrocyte shape and mechanical property regulation. Mutations in the EPB42 gene are associated with recessive spherocytic elliptocytosis and recessively transmitted hereditary hemolytic anemia.
Alias Symbols: PA, SPH5
Protein Interaction Partner: MAPK14, SPINK7, BLOC1S4, STX12, CD47, SLC4A2, KRAS, ANK1, SPTAN1, EPB41, DMTN, SLC4A1, ANK2,
Protein Size: 721

Molecular Weight: 80 kDa

Gene ID: 2038

NCBI Accession: NM_000119, NP_000110

Pathways: Transition Metal Ion Homeostasis