Cholecystokinin antibody (Middle Region)

Catalog No. ABIN2778154

This Rabbit Polyclonal antibody specifically detects Cholecystokinin in WB. It exhibits reactivity toward Human, Rat, Mouse, Dog, Pig, Cow, Guinea Pig, Horse and Rabbit and has been mentioned in 2+ publications.

Quick Overview for Cholecystokinin antibody (Middle Region) (ABIN2778154)

Target: Cholecystokinin (CCK)

Reactivity: Human, Rat, Mouse, Dog, Pig, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cholecystokinin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cholecystokinin Antibody

Binding Specificity: Middle Region

Sequence: IQQARKAPSG RMSIVKNLQN LDPSHRISDR DYMGWMDFGR RSAEEYEYPS

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 86%, Rabbit: 86%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against CCK. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CCK

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 115 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Cholecystokinin antibody (ABIN2778154)

Talchai, Xuan, Kitamura, DePinho, Accili: "Generation of functional insulin-producing cells in the gut by Foxo1 ablation." in: Nature genetics, Vol. 44, Issue 4, pp. 406-12, S1, (2012) (PubMed).

Roskos, Wallace, Weiss: "Readability of consumer medication information for intranasal corticosteroid inhalers." in: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, Vol. 65, Issue 1, pp. 65-8, (2007) (PubMed).

Target Details for Cholecystokinin

Target: Cholecystokinin (CCK)

Alternative Name: CCK

Background: Cholecystokinin (CCK) is a brain/gut peptide. In the gut, it induces the release of pancreatic enzymes and the contraction of the gallbladder. In the brain, its physiologic role is unclear. The cholecystokinin pro-hormone is processed by endo- and exo-proteolytic cleavages.Cholecystokinin is a brain/gut peptide. In the gut, it induces the release of pancreatic enzymes and the contraction of the gallbladder. In the brain, its physiologic role is unclear. The cholecystokinin pro-hormone is processed by endo- and exo-proteolytic cleavages. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC117187
Protein Interaction Partner: UBC, CCKBR, CCKAR, CPE, ENPEP, MEP1B, MEP1A,
Protein Size: 115

Molecular Weight: 13 kDa

Gene ID: 885

NCBI Accession: NM_000729, NP_000720

UniProt: P06307

Pathways: TCR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades, Feeding Behaviour