Chymotrypsin antibody (N-Term)

Catalog No. ABIN2778163

This anti-Chymotrypsin antibody is a Rabbit Polyclonal antibody detecting Chymotrypsin in WB. Suitable for Human, Mouse, Rat, Dog and Pig.

Quick Overview for Chymotrypsin antibody (N-Term) (ABIN2778163)

Target: Chymotrypsin (CTRL)

Reactivity: Human, Mouse, Rat, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Chymotrypsin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Chymotrypsin Antibody

Binding Specificity: N-Term

Sequence: LLLSLTLSLV LLGSSWGCGI PAIKPALSFS QRIVNGENAV LGSWPWQVSL

Predicted Reactivity: Dog: 100%, Human: 100%, Mouse: 85%, Pig: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CTRL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CTRL

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 264 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Chymotrypsin

Target: Chymotrypsin (CTRL)

Alternative Name: CTRL

Target Type: Chemical

Background: CTRL contains 1 F-box domain. It is substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.The protein directly interacts with SKP1A and CUL1. A chromosomal aberration involving FBXO25 is a cause of X-linked mental retardation (XLMR).
Alias Symbols: CTRL1, MGC70821
Protein Interaction Partner: SERPINA3,
Protein Size: 264

Molecular Weight: 25 kDa

Gene ID: 1506

NCBI Accession: NM_001907, NP_001898

UniProt: P40313