BRDT antibody (N-Term)

Catalog No. ABIN2778228

This Rabbit Polyclonal antibody specifically detects BRDT in WB. It exhibits reactivity toward Human, Guinea Pig, Cow, Horse, Mouse, Rabbit, Rat, Dog and Zebrafish (Danio rerio).

Quick Overview for BRDT antibody (N-Term) (ABIN2778228)

Target: BRDT (Bromodomain, Testis-Specific (BRDT))

Reactivity: Human, Guinea Pig, Cow, Horse, Mouse, Rabbit, Rat, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRDT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BRDT Antibody

Binding Specificity: N-Term

Sequence: NPPPPEYINT KKNGRLTNQL QYLQKVVLKD LWKHSFSWPF QRPVDAVKLQ

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against BRDT. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human BRD4

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BRDT

Target: BRDT (Bromodomain, Testis-Specific (BRDT))

Alternative Name: BRDT

Background: The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15,19)(q13,p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.
Alias Symbols: CAP, MCAP, HUNK1, HUNKI
Protein Size: 462

Molecular Weight: 50 kDa

Gene ID: 23476

NCBI Accession: NM_014299, NP_055114

UniProt: O60885