CUX1 antibody (N-Term)

Catalog No. ABIN2778283

This anti-CUX1 antibody is a Rabbit Polyclonal antibody detecting CUX1 in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Guinea Pig and Rabbit. This Primary Antibody has been cited in 1 publication.

Quick Overview for CUX1 antibody (N-Term) (ABIN2778283)

Target: CUX1 (Cut-Like Homeobox 1 (CUX1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CUX1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CUX1 Antibody

Binding Specificity: N-Term

Sequence: VKNQEVTIKA LKEKIREYEQ TLKNQAETIA LEKEQKLQND FAEKERKLQE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CUX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CUX1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 678 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CUX1 antibody (ABIN2778283)

Truscott, Harada, Vadnais, Robert, Nepveu: "p110 CUX1 cooperates with E2F transcription factors in the transcriptional activation of cell cycle-regulated genes." in: Molecular and cellular biology, Vol. 28, Issue 10, pp. 3127-38, (2008) (PubMed).

Target Details for CUX1

Target: CUX1 (Cut-Like Homeobox 1 (CUX1))

Alternative Name: CUX1

Background: The protein encoded by this gene is a member of the homeodomain family of DNA binding proteins. It may regulate gene expression, morphogenesis, and differentiation and it may also play a role in the cell cycle progession. Several alternatively spliced tra
Alias Symbols: CASP, CDP, CDP/Cut, CDP1, COY1, CUTL1, CUX, Clox, Cux/CDP, GOLIM6, Nbla10317, p100, p110, p200, p75
Protein Interaction Partner: UBC, SOX2, TP53BP1, ECT2, EHMT2, KCND3, SUMO2, TLE4, MAX, CA12, CYTH2, SATB1, BIN1, CREBBP, SDC3, RB1, HMGB1, CDC25A, CDK1, CTSL, KAT2B, GOLGA5, ELAC2, RECQL5, CCNA1, CDK7,
Protein Size: 678

Molecular Weight: 77 kDa

Gene ID: 1523

NCBI Accession: NM_001913, NP_001904

UniProt: Q13948

Pathways: Cellular Glucan Metabolic Process