RBBP5 antibody (Middle Region)

Catalog No. ABIN2778328

This Rabbit Polyclonal antibody specifically detects RBBP5 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Horse, Dog, Rabbit and Pig.

Quick Overview for RBBP5 antibody (Middle Region) (ABIN2778328)

Target: RBBP5 (Retinoblastoma Binding Protein 5 (RBBP5))

Reactivity: Human, Mouse, Rat, Cow, Horse, Dog, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBBP5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RBBP5 Antibody

Binding Specificity: Middle Region

Sequence: GASSEKKRQS SADGSQPPKK KPKTTNIELQ GVPNDEVHPL LGVKGDGKSK

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RBBP5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RBBP5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 538 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RBBP5

Target: RBBP5 (Retinoblastoma Binding Protein 5 (RBBP5))

Alternative Name: RBBP5

Background: RBBP5 contains 6 WD repeats. It binds preferentially to underphosphorylated retinoblastoma protein. The protein encoded by this gene is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1 AU099032.1 13-13 2-26 CD710496.1 39-63 27-567 BC053856.1 17-557 568-1604 BC037284.2 540-1576 1605-2978 BC053856.1 1595-2968 2979-2979 BC037284.2 2838-2838 2980-2992 AA235403.1 1-13 2993-3136 BC037284.2 2851-2994 3137-3318 BC053856.1 3125-3306 3319-3334 BC037284.2 3177-3192 3335-3342 BG392257.1 177-184 3343-3587 BC037284.2 3200-3444 3588-3683 CB133829.1 341-436
Alias Symbols: RBQ3, SWD1
Protein Interaction Partner: CXXC1, SETD1A, ASH2L, PPARG, KMT2A, KMT2D, SENP3, UBE2I, UBC, SUMO2, Fbxl16, KDM6B, KDM6A, SMARCD1, KLC2, SRRT, DHX38, SMARCE1, SMARCD2, HCFC1, SMARCC1, MEN1, USF1, WDR5, ELAVL1, ESR1, KANSL1, DPY30, KDM4B, KMT2B, PSMA3, CTBP1, TBK1, CDC73, HIST3H3, PYGO2
Protein Size: 538

Molecular Weight: 59 kDa

Gene ID: 5929

NCBI Accession: NM_005057, NP_005048

UniProt: Q15291