MXD3 antibody (N-Term)

Catalog No. ABIN2778375

This Rabbit Polyclonal antibody specifically detects MXD3 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio) and Sheep.

Quick Overview for MXD3 antibody (N-Term) (ABIN2778375)

Target: MXD3 (MAX Dimerization Protein 3 (MXD3))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio), Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MXD3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MXD3 Antibody

Binding Specificity: N-Term

Sequence: MEPLASNIQV LLQAAEFLER REREAEHGYA SLCPHRSPGP IHRRKKRPPQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against MXD3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MXD3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 206 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MXD3

Target: MXD3 (MAX Dimerization Protein 3 (MXD3))

Alternative Name: MXD3

Background: MXD3 contains 1 basic helix-loop-helix (bHLH) domain. It is a transcriptional repressor and binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.
Alias Symbols: MAD3, MGC2383, MYX, BHLHC13
Protein Interaction Partner: NOTCH2NL, KRTAP10-7, UBC, NFKB1, MAGEA11, MAX, SIN3A, SMC3,
Protein Size: 206

Molecular Weight: 23 kDa

Gene ID: 83463

NCBI Accession: NM_031300, NP_112590

UniProt: Q9BW11