OTP antibody (C-Term)

Catalog No. ABIN2778383

This Rabbit Polyclonal antibody specifically detects OTP in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Guinea Pig and Zebrafish (Danio rerio)and has been mentioned in 1 publication.

Quick Overview for OTP antibody (C-Term) (ABIN2778383)

Target: OTP (Orthopedia Homeobox (OTP))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OTP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-OTP Antibody

Binding Specificity: C-Term

Sequence: PAFPGMVPAS LPGPSNVSGS PQLCSSPDSS DVWRGTSIAS LRRKALEHTV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against OTP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human OTP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 325 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-OTP antibody (ABIN2778383)

Metwalli, Abellán, Freixes, Pross, Desfilis, Medina: "Distinct Subdivisions in the Transition Between Telencephalon and Hypothalamus Produce Otp and Sim1 Cells for the Extended Amygdala in Sauropsids." in: Frontiers in neuroanatomy, Vol. 16, pp. 883537, (2022) (PubMed).

Target Details for OTP

Target: OTP (Orthopedia Homeobox (OTP))

Alternative Name: OTP

Background: OTP is a member of the homeodomain (HD) family. HD family proteins are helix-turn-helix transcription factors that play key roles in the specification of cell fates. This protein may function during brain development.This gene encodes a member of the homeodomain (HD) family. HD family proteins are helix-turn-helix transcription factors that play key roles in the specification of cell fates. This protein may function during brain development.
Protein Size: 325

Molecular Weight: 34 kDa

Gene ID: 23440

NCBI Accession: NM_032109, NP_115485

UniProt: Q5XKR4