ZNF384 antibody (C-Term)

Catalog No. ABIN2778449

This anti-ZNF384 antibody is a Rabbit Polyclonal antibody detecting ZNF384 in WB. Suitable for Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Mouse.

Quick Overview for ZNF384 antibody (C-Term) (ABIN2778449)

Target: ZNF384 (Zinc Finger Protein 384 (ZNF384))

Reactivity: Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF384 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ZNF384 Antibody

Binding Specificity: C-Term

Sequence: QQPPPHFQSP GAAPQGGGGG DSNPNPPPQC SFDLTPYKTA EHHKDICLTV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ZNF384. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 461 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ZNF384

Target: ZNF384 (Zinc Finger Protein 384 (ZNF384))

Alternative Name: ZNF384

Background: This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7.
Alias Symbols: CAGH1, CAGH1A, CIZ, ERDA2, FLJ59043, NMP4, NP, TNRC1
Protein Interaction Partner: SOX2, UBC, OPTN, tat, HOXC9, CEBPE, TAF15, ZYX, PCBP1, VIM,
Protein Size: 461

Molecular Weight: 50 kDa

Gene ID: 171017

NCBI Accession: NM_001039920, NP_001035009