EHF antibody (N-Term)
Quick Overview for EHF antibody (N-Term) (ABIN2778625)
Target
See all EHF AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- SCIPFQEFDI SGEHLCSMSL QEFTRAAGSA GQLLYSNLQH LKWNGQCSSD
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Predicted Reactivity
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 93%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 93%
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Characteristics
- This is a rabbit polyclonal antibody against Ehf. It was validated on Western Blot and immunohistochemistry.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of mouse Ehf
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 300 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Profile of Ets gene expression in human breast carcinoma." in: Cancer biology & therapy, Vol. 6, Issue 1, pp. 76-82, (2007) (PubMed).
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: "Profile of Ets gene expression in human breast carcinoma." in: Cancer biology & therapy, Vol. 6, Issue 1, pp. 76-82, (2007) (PubMed).
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- EHF (Ets Homologous Factor (EHF))
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Alternative Name
- Ehf
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Background
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Ehf is a transcriptional activator that may play a role in regulating epithelial cell differentiation and proliferation. It may act as a repressor for a specific subset of ETS/AP-1-responsive genes, and as a modulator of the nuclear response to mitogen-activated protein kinase signaling cascades. It binds to DNA sequences containing the consensus nucleotide core sequence GGAA and involved in regulation of TNFRSF10B/DR5 expression through Ets-binding sequences on the TNFRSF10B/DR5 promoter
Alias Symbols: 9030625L19Rik, AU019492
Protein Interaction Partner: Nfkbiz,
Protein Size: 300 -
Molecular Weight
- 33 kDa
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Gene ID
- 13661
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NCBI Accession
- NM_007914, NP_031940
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UniProt
- Q9NZC4
Target
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