TUBA4A antibody (Middle Region)

Catalog No. ABIN2778649

This Rabbit Polyclonal antibody specifically detects TUBA4A in WB, IHC and IP. It exhibits reactivity toward Human, Mouse, Rat, Dog, Sheep, Cow, Rabbit, Guinea Pig and Horse.

Quick Overview for TUBA4A antibody (Middle Region) (ABIN2778649)

Target: TUBA4A (Tubulin, alpha 4a (TUBA4A))

Reactivity: Human, Mouse, Rat, Dog, Sheep, Cow, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUBA4A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-TUBA4A Antibody

Binding Specificity: Middle Region

Sequence: YAKRAFVHWY VGEGMEEGEF SEAREDMAAL EKDYEEVGID SYEDEDEGEE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against TUBA4A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TUBA4A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 448 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TUBA4A

Target: TUBA4A (Tubulin, alpha 4a (TUBA4A))

Alternative Name: TUBA4A

Background: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene encodes an alpha tubulin that is a highly conserved homolog of a rat testis-specific alpha tubulin.Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene encodes an alpha tubulin that is a highly conserved homolog of a rat testis-specific alpha tubulin. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ30169, H2-ALPHA, TUBA1
Protein Interaction Partner: MAPT, CDC20, HAUS1, CEP76, HAUS2, MAGED2, TUBGCP2, CEP57, UBC, TUBG1, TP53, SUMO2, STAU1, MDM2, MGRN1, RPA3, RPA2, RPA1, rev, TUBB, TUBA1C, TUBB6, TUBA4B, TUBB4B, TUBA1A, TXNRD1, TUBB2A, RPS27A, PRPS1, YBX1, HSPA5, HSPA1A, CRYZ, PARK2, EGFR, SOX2, ICAM1,
Protein Size: 448

Molecular Weight: 50 kDa

Gene ID: 7277

NCBI Accession: NM_006000, NP_005991

UniProt: P68366

Pathways: Microtubule Dynamics, M Phase