EXOSC3 antibody (Middle Region)

Catalog No. ABIN2778687

This Rabbit Polyclonal antibody specifically detects EXOSC3 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse and Rabbit.

Quick Overview for EXOSC3 antibody (Middle Region) (ABIN2778687)

Target: EXOSC3 (Exosome Component 3 (EXOSC3))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXOSC3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-EXOSC3 Antibody

Binding Specificity: Middle Region

Sequence: TKCGRLRHKE PGSGSGGGVY WVDSQQKRYV PVKGDHVIGI VTAKSGDIFK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against EXOSC3. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EXOSC3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 275 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EXOSC3

Target: EXOSC3 (Exosome Component 3 (EXOSC3))

Alternative Name: EXOSC3

Background: EXOSC3 is component of the exosome 3'->5' exoribonuclease complex and is required for the 3' processing of the 7S pre-RNA to the mature 5.8S rRNA.
Alias Symbols: p10, RRP40, Rrp40p, CGI-102, hRrp-40, hRrp40p, bA3J10.7, RP11-3J10.8
Protein Interaction Partner: UBC, EXOSC5, EXOSC4, CDK5RAP1, EXOSC8, ATP5D, AICDA, EXOSC10, EXOSC9, APP, EXOSC2, EXOSC6, DIS3L, EXOSC1, EXOSC3, EXOSC7, DIS3, MPHOSPH6, HDGF, KHSRP,
Protein Size: 275

Molecular Weight: 30 kDa

Gene ID: 51010

NCBI Accession: NM_016042, NP_057126

UniProt: Q9NQT5

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome