U2AF2 antibody (C-Term)

Catalog No. ABIN2778723

This anti-U2AF2 antibody is a Rabbit Polyclonal antibody detecting U2AF2 in WB. Suitable for Human, Mouse, Rat, Cow, Horse, Dog, Guinea Pig, Zebrafish (Danio rerio) and Saccharomyces cerevisiae.

Quick Overview for U2AF2 antibody (C-Term) (ABIN2778723)

Target: U2AF2 (U2AF59) (U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59))

Reactivity: Human, Mouse, Rat, Cow, Horse, Dog, Guinea Pig, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This U2AF2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-U2AF2 Antibody

Binding Specificity: C-Term

Sequence: TEVLCLMNMV LPEELLDDEE YEEIVEDVRD ECSKYGLVKS IEIPRPVDGV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against U2AF2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human U2AF2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 471 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for U2AF2

Target: U2AF2 (U2AF59) (U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59))

Alternative Name: U2AF2

Background: U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2AF2 is the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly.
Alias Symbols: U2AF65
Protein Interaction Partner: THAP1, PUF60, U2AF1, SNRPA, AES, DACH1, SUMO3, UBC, SUZ12, EED, TERF1, EZH2, RNF2, PRPF40A, TCERG1, APBB1, PIN1, SH3RF2, SRPK2, SRPK1, SF1, SRSF1, RBM39, QKI, SCAF11, PRPF3, RBM10, RBM4, SMAD5, IL7R, HNRNPK, HNRNPD, HLA-DMA, SUGP1, CCAR1, SAP30BP, RBFOX2,
Protein Size: 471

Molecular Weight: 53 kDa

Gene ID: 11338

NCBI Accession: NM_001012478, NP_001012496

UniProt: Q80XR5