FXR1 antibody (C-Term)
Quick Overview for FXR1 antibody (C-Term) (ABIN2778725)
Target
See all FXR1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Sequence
- EQLRQIGSRS YSGRGRGRRG PNYTSGYGTN SELSNPSETE SERKDELSDW
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Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Characteristics
- This is a rabbit polyclonal antibody against FXR1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human FXR1
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 621 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FXR1 (Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1))
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Alternative Name
- FXR1
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Background
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FXR1 is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit.The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FXR1P
Protein Interaction Partner: UBC, TOP3B, FXR2, ORC2, CAPRIN1, FMR1, LRWD1, TDRD3, UBAP2, RANBP9, SUZ12, BMI1, CSNK2A1, CAND1, COPS5, CUL3, SIRT7, ELAVL1, SUMO2, SUMO1, HDAC5, GIGYF2, LRIF1, LUC7L2, KIAA1377, CYFIP2, PRSS23, C14orf1, CRMP1, FXR1, GBP2, CYFIP1,
Protein Size: 621 -
Molecular Weight
- 68 kDa
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Gene ID
- 8087
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NCBI Accession
- NM_005087, NP_005078
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UniProt
- P51114
Target
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