NCBP1 antibody (N-Term)

Catalog No. ABIN2778796

The Rabbit Polyclonal anti-NCBP1 antibody has been validated for WB. It is suitable to detect NCBP1 in samples from Human, Mouse, Rat, Cow, Dog, Rabbit and Pig.

Quick Overview for NCBP1 antibody (N-Term) (ABIN2778796)

Target: NCBP1 (Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCBP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NCBP1 Antibody

Binding Specificity: N-Term

Sequence: SRRRHSDEND GGQPHKRRKT SDANETEDHL ESLICKVGEK SACSLESNLE

Predicted Reactivity: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 88%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against NCBP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NCBP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 790 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NCBP1

Target: NCBP1 (Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1))

Alternative Name: NCBP1

Background: NCBP1 is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay.The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CBP80, MGC2087, NCBP, Sto1
Protein Interaction Partner: POLDIP3, HUWE1, EIF4G1, UPF3B, EIF3B, MTOR, RPS6KB1, ALYREF, DDX39B, THOC3, THOC2, IVNS1ABP, UBC, LIN28B, LIN28A, ZNF346, SUMO1, SUZ12, EED, RNF2, BMI1, VAT1, MVP, TTC1, PPM1G, SERPINE2, NCL, NAP1L4, GFPT1, GARS, PUS1, TARDBP, YWHAE, RUVBL1, MPG, FN1, C17
Protein Size: 790

Molecular Weight: 92 kDa

Gene ID: 4686

NCBI Accession: NM_002486, NP_002477

UniProt: Q09161

Pathways: Ribonucleoprotein Complex Subunit Organization, Photoperiodism, Methionine Biosynthetic Process