RBMS1 antibody (C-Term)

Catalog No. ABIN2778818

The Rabbit Polyclonal anti-RBMS1 antibody has been validated for WB and IHC. It is suitable to detect RBMS1 in samples from Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow and Goat.

Quick Overview for RBMS1 antibody (C-Term) (ABIN2778818)

Target: RBMS1 (RNA Binding Motif, Single Stranded Interacting Protein 1 (RBMS1))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBMS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RBMS1 Antibody

Binding Specificity: C-Term

Sequence: TYMPATSAMQ GAYLPQYAHM QTTAVPVEEA SGQQQVAVET SNDHSPYTFQ

Predicted Reactivity: Cow: 93%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RBMS1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RBMS1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 403 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RBMS1

Target: RBMS1 (RNA Binding Motif, Single Stranded Interacting Protein 1 (RBMS1))

Alternative Name: RBMS1

Background: RBMS1 is a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis.This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Multiple transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. Several of these were isolated by virtue of their binding to either strand of an upstream element of c-myc (MSSPs), or by phenotypic complementation of cdc2 and cdc13 mutants of yeast (scr2), or as a potential human repressor of HIV-1 and ILR-2 alpha promoter transcription (YC1). A pseudogene for this locus is found on chromosome 12.
Alias Symbols: YC1, MSSP, SCR2, HCC-4, MSSP-1, MSSP-2, MSSP-3, C2orf12
Protein Interaction Partner: TFCP2, UBC, MRPL53, MRRF, SARNP, NABP2, SRPRB, SUGP1, SBDS, UBQLN1, TIMM44, HRSP12, PPIF, PQBP1, ZC3H11A, SNX3, STX7, UBE2I, SNRPC, SCP2, RRBP1, RPS19, RPL38, RFX5, PPIB, NDUFA7, DNM2, GRK5, POLA1,
Protein Size: 403

Molecular Weight: 44 kDa

Gene ID: 5937

NCBI Accession: NM_002897, NP_002888