GRP94 antibody (C-Term)

Catalog No. ABIN2778847

This Rabbit Polyclonal antibody specifically detects GRP94 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Rabbit, Pig, Horse, Zebrafish (Danio rerio) and Saccharomyces cerevisiae.

Quick Overview for GRP94 antibody (C-Term) (ABIN2778847)

Target: GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Pig, Horse, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRP94 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GRP94 Antibody

Binding Specificity: C-Term

Sequence: EEEPEEEPEE TAEDTTEDTE QDEDEEMDVG TDEEEETAKE STAEKDEL

Predicted Reactivity: Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 85%, Pig: 93%, Rabbit: 86%, Rat: 93%, Yeast: 100%, Zebrafish: 81%

Characteristics: This is a rabbit polyclonal antibody against HSP90B1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HSP90B1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 803 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GRP94

Target: GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))

Alternative Name: HSP90B1

Background: HSP90B1 belongs to the heat shock protein 90 family. It is molecular chaperone that functions in the processing and transport of secreted proteins.
Alias Symbols: ECGP, GP96, GRP94, TRA1
Protein Interaction Partner: ERLIN2, HUWE1, HDAC6, UBC, FUS, TRIM68, SUMO2, CLU, NEDD8, MDM2, EED, rev, TPM1, KIAA1598, KIAA1468, CDC37L1, PHAX, USP25, CAP1, MCM3, PARK2, EGFR, UBD, MLLT3, ADRB2, MAPK7, LYN, KDM4B, METTL23, env, TXNDC11, IQCB1, KCNQ4, ATF2, NKX3-1, OS9, CCT2, AIMP1,
Protein Size: 803

Molecular Weight: 90 kDa

Gene ID: 7184

NCBI Accession: NM_003299, NP_003290

UniProt: P14625

Pathways: Thyroid Hormone Synthesis, Activation of Innate immune Response, ER-Nucleus Signaling, Toll-Like Receptors Cascades