HNRNPC antibody (Middle Region)

Catalog No. ABIN2778890

This anti-HNRNPC antibody is a Rabbit Polyclonal antibody detecting HNRNPC in WB and IHC. Suitable for Human, Rat, Mouse, Rabbit, Cow, Dog, Horse, Zebrafish (Danio rerio), Goat, Guinea Pig and Saccharomyces cerevisiae.

Quick Overview for HNRNPC antibody (Middle Region) (ABIN2778890)

Target: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Reactivity: Human, Rat, Mouse, Rabbit, Cow, Dog, Horse, Zebrafish (Danio rerio), Goat, Guinea Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-HNRNPC Antibody

Binding Specificity: Middle Region

Sequence: ESEGGADDSA EEGDLLDDDD NEDRGDDQLE LIKDDEKEAE EGEDDRDSAN

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against HNRNPC. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HNRNPC

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 306 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HNRNPC

Target: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Alternative Name: HNRNPC

Background: This protein is associated with pre-mRNAs in the nucleus and appears to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein acts as a tetramer and is involved in the assembly of 40S hnRNP particles. This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene.
Alias Symbols: C1, C2, HNRNP, HNRPC, MGC104306, MGC105117, MGC117353, MGC131677, SNRPC
Protein Interaction Partner: SUMO1P1, RALYL, RBM41, ZFYVE26, SUMO1, UBE2I, UBC, SDCBP, LMO2, KPNA4, KPNA3, KPNA2, HNRNPC, EPS8, BRIP1, PALB2, BRCA2, BRCA1, BARD1, CEP250, SUMO2, SUMO3, RAD51, IVNS1ABP, STAU1, MDM2, ERG, EED, RNF2, rev, CDKN2A, PARK2, SRPK2, SRPK1, CLK3, TARDBP, YWHAQ
Protein Size: 306

Molecular Weight: 34 kDa

Gene ID: 3183

NCBI Accession: NM_031314, NP_112604

UniProt: P07910