TRA2B antibody (N-Term)

Catalog No. ABIN2778898

This anti-TRA2B antibody is a Rabbit Polyclonal antibody detecting TRA2B in WB and IHC. Suitable for Human, Mouse, Dog, Rat, Cow, Horse, Rabbit and Pig. This Primary Antibody has been cited in 1 publication.

Quick Overview for TRA2B antibody (N-Term) (ABIN2778898)

Target: TRA2B (Transformer 2 beta Homolog (TRA2B))

Reactivity: Human, Mouse, Dog, Rat, Cow, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRA2B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TRA2B Antibody

Binding Specificity: N-Term

Sequence: MSDSGEQNYG ERESRSASRS GSAHGSGKSA RHTPARSRSK EDSRRSRSKS

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SFRS10. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SFRS10

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 288 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TRA2B antibody (ABIN2778898)

Fu, Mende, Bhetwal, Baker, Perrino, Wirth, Fisher: "Tra2? protein is required for tissue-specific splicing of a smooth muscle myosin phosphatase targeting subunit alternative exon." in: The Journal of biological chemistry, Vol. 287, Issue 20, pp. 16575-85, (2012) (PubMed).

Target Details for TRA2B

Target: TRA2B (Transformer 2 beta Homolog (TRA2B))

Alternative Name: SFRS10

Background: SFRS10 contains 1 RRM (RNA recognition motif) domain and belongs to the splicing factor SR family. It is a sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing.
Alias Symbols: SFRS10, SRFS10, TRAN2B, TRA2-BETA, Htra2-beta
Protein Interaction Partner: SUMO3, SUMO2, EED, CLK3, SRPK2, SRPK1, YWHAE, HNRNPA1, CDK6, YTHDC1, RBMX, RNPS1, SRSF10, NXF1, UBC, SRSF6, SRSF4, SRSF3, SRSF2, MAGOH, EIF4A3, BARD1, PAXIP1, PPP4R2, SF3B1, FAF2, PSIP1, GCN1L1, EIF4H, SRSF7, SRSF5, SRSF1, S100A9, RBMS2, RAN, PRKDC, NHP2L
Protein Size: 288

Molecular Weight: 32 kDa

Gene ID: 6434

NCBI Accession: NM_004593, NP_004584

UniProt: P62995