ZRSR2 antibody (C-Term)

Catalog No. ABIN2778926

This Rabbit Polyclonal antibody specifically detects ZRSR2 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Horse, Dog, Cow, Rabbit and Guinea Pig.

Quick Overview for ZRSR2 antibody (C-Term) (ABIN2778926)

Target: ZRSR2 (Zinc Finger (CCCH Type), RNA-Binding Motif and serine/arginine Rich 2 (ZRSR2))

Reactivity: Human, Mouse, Rat, Horse, Dog, Cow, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZRSR2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ZRSR2 Antibody

Binding Specificity: C-Term

Sequence: HHDDYYSRLR GRRNPSPDHS YKRNGESERK SSRHRGKKSH KRTSKSRERH

Predicted Reactivity: Cow: 83%, Dog: 92%, Guinea Pig: 100%, Horse: 79%, Human: 100%, Mouse: 90%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ZRSR2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ZRSR2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 482 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ZRSR2

Target: ZRSR2 (Zinc Finger (CCCH Type), RNA-Binding Motif and serine/arginine Rich 2 (ZRSR2))

Alternative Name: ZRSR2

Background: ZRSR2 is an essential splicing factor. The protein associates with the U2 auxiliary factor heterodimer, which is required for the recognition of a functional 3' splice site in pre-mRNA splicing, and may play a role in network interactions during spliceosome assembly.This gene encodes U2AF small subunit related protein 2 which is an essential splicing factor. This protein is associated with the U2AF heterodimer composed of a large and a small subunit. It specifically interacts with the large subunit through an U2AF small subunit homologous region, and with SR proteins through its RS domain. This protein and U2AF small subunit are not functionally redundant.
Alias Symbols: URP, U2AF1L2, U2AF1RS2, U2AF1-RS2
Protein Interaction Partner: CLK2, SSX2IP, SDCBP2, SRPK2, UBC, SRPK1, APP, SRSF2, SRSF1, U2AF2, U2AF1,
Protein Size: 482

Molecular Weight: 53 kDa

Gene ID: 8233

NCBI Accession: NM_005089, NP_005080

UniProt: Q15696

Pathways: Ribonucleoprotein Complex Subunit Organization