BCAS2 antibody (N-Term)

Catalog No. ABIN2778957

This Rabbit Polyclonal antibody specifically detects BCAS2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse and Zebrafish (Danio rerio)and has been mentioned in 1 publication.

Quick Overview for BCAS2 antibody (N-Term) (ABIN2778957)

Target: BCAS2 (Breast Carcinoma Amplified Sequence 2 (BCAS2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCAS2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BCAS2 Antibody

Binding Specificity: N-Term

Sequence: MAGTGLVAGE VVVDALPYFD QGYEAPGVRE AAAALVEEET RRYRPTKNYL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against BCAS2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human BCAS2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 225 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-BCAS2 antibody (ABIN2778957)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for BCAS2

Target: BCAS2 (Breast Carcinoma Amplified Sequence 2 (BCAS2))

Alternative Name: BCAS2

Background: BCAS2 belongs to the SPF27 family. It is involved in mRNA splicing. The protein might play an important role in breast cancer development by increasing the estrogen receptor's function.
Alias Symbols: DAM1, SPF27, Snt309
Protein Interaction Partner: GOLGA2, KRT40, IKZF3, HGS, AIMP2, TCF4, UBC, RPA3, RPA2, RPA1, SUZ12, EED, RNF2, CSNK2A2, TXNRD2, PPARG, PGR, ESR2, ESR1, POT1, PRPF8, SF3B4, SF1, EP300, CDC5L, PRPF19, EIF4A3, MAGOH, VASN, SF3B6, NCSTN, SNRNP200, ACIN1, HNRNPA0, SRSF10, RBM39, EFTUD2, PR
Protein Size: 225

Molecular Weight: 26 kDa

Gene ID: 10286

NCBI Accession: NM_005872, NP_005863

UniProt: O75934