GNB2L1 antibody (N-Term)

Catalog No. ABIN2778965

The Rabbit Polyclonal anti-GNB2L1 antibody is suitable to detect GNB2L1 in samples from Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit, Sheep, Zebrafish (Danio rerio) and Saccharomyces cerevisiae. It has been validated for WB and IHC.

Quick Overview for GNB2L1 antibody (N-Term) (ABIN2778965)

Target: GNB2L1 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit, Sheep, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNB2L1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GNB2L1 Antibody

Binding Specificity: N-Term

Sequence: ISSDGQFALS GSWDGTLRLW DLTTGTTTRR FVGHTKDVLS VAFSSDNRQI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against GNB2L1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GNB2L1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 317 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GNB2L1

Target: GNB2L1 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1))

Alternative Name: GNB2L1

Background: GNB2L1 seems to bind protein kinase C acting as an intracellular receptor to anchor the activated PKC to the cytoskeleton. GNB2L1 may be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and ITGB1, GNB2L1 serves as a platform for SRC activation or inactivation. GNB2L1 may play an important role in the developing brain and neuronal differentiation.
Alias Symbols: Gnb2-rs1, H12.3, HLC-7, PIG21, RACK1
Protein Interaction Partner: MKRN2, LARP4B, HUWE1, UBC, SUMO2, HIF1A, STAU1, TARDBP, ADRB2, PRKCB, TRIM45, RNF2, EZH2, BMI1, SUZ12, rev, PTOV1, RPS8, RPS6, RPS5, RPS3A, RPS27L, EIF3K, SYNCRIP, DYNLL1, RPS3, RPSA, EIF3E, DYNC1LI2, RPS9, RPS27, RPS21, RPS20, RPS18, RPS16, RPS13, RPS12,
Protein Size: 317

Molecular Weight: 35 kDa

Gene ID: 10399

NCBI Accession: NM_006098, NP_006089

UniProt: P63244

Pathways: cAMP Metabolic Process, Positive Regulation of Endopeptidase Activity